
Luca Signorelli (c. 1450–1523) painted the human body with a power that directly inspired Michelangelo. Born Luca d'Egidio di Ventura in Cortona, Tuscany, he trained under Piero della Francesca and absorbed that master's geometric clarity. But Signorelli rejected Piero's calm, still figures. He wanted bodies in violent motion, muscles straining, limbs twisting. Some historians believe he studied under Antonio Pollaiuolo, whose obsession with anatomy showed in every sinew and tendon.
Signorelli worked across central Italy: Loreto, Perugia, Urbino, Rome. Around 1483 he painted the Testament of Moses fresco in the Sistine Chapel, joining other masters decorating the walls that Michelangelo would later crown. But his masterpiece came at Orvieto Cathedral. Between 1499 and 1503, he covered the Cappella di San Brizio with frescoes of the Last Judgment, the Apocalypse, and the Resurrection of the Flesh. The contract, still preserved, promised him 600 ducats plus lodging, wine, and corn. Theological advisors guided his iconography, the first documented instance of such collaboration. His demons torture the damned with horrifying creativity. His nude figures, male and female, display anatomy studied from dissected corpses.
Tragedy struck during the Orvieto commission: Signorelli's son Antonio died of plague. According to Vasari, he painted the dead Christ using his son's body as the model. Signorelli remained active in Cortona politics, serving on the town council, until his death in 1523 at nearly eighty. Renaissance painters studied his Orvieto frescoes for generations. Works survive at the Uffizi, the National Gallery, and the Louvre.
13 paintings catalogued with museum locations

Luca Signorelli, 1500
Orvieto Cathedral, Orvieto

Luca Signorelli
Basilica della Santa Casa, Loreto, Loreto

Luca Signorelli
Uffizi Gallery, Florence, Florence

Luca Signorelli
Pinacoteca di Brera, Milan

Luca Signorelli
Uffizi Gallery, Florence, Florence

Luca Signorelli
Basilica della Santa Casa, Loreto, Loreto

Luca Signorelli
Private Collection, Unknown

Luca Signorelli
Basilica della Santa Casa, Loreto, Loreto

Luca Signorelli
Private Collection, Unknown

Luca Signorelli
Basilica della Santa Casa, Loreto, Loreto

Luca Signorelli
Uffizi Gallery, Florence, Florence

Luca Signorelli
Basilica della Santa Casa, Loreto, Loreto

Luca Signorelli
Basilica of San Francesco, Arezzo, Arezzo
6 museums display Signorelli's works. Click any museum to see visiting info and the specific works they hold.


Unknown, Unknown
2 works on display
Scenes from the Lives of Joachim and Anne
The Birth of the Virgin



Florence, Italy
3 works on display
The Crucifixion with St. Mary Magdalen
Madonna and Child with Prophets

Milan, Italy
1 work on display
The Flagellation



Loreto, Italy
5 works on display
Pair of Apostles in Dispute
Christ and the Doubting Thomas

Arezzo, Italy
1 work on display
Annunciation

Orvieto, Italy
1 work on display
The Damned Cast into Hell
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